MILWAUKEE — Jason Isringhausen got his wish.

After blowing his major league-leading fifth save on Friday night in a 4-3 loss to the Milwaukee Brewers, the Cardinals’ embattled reliever will no longer close games, manager Tony La Russa said Saturday.

“He’s still prepared to pitch important innings, but for a while we’ll try to keep him out of the ninth inning,” La Russa said. “If we’re playing well, there’s still going to be games where you can’t cherry pick his situations because if we’re playing well, you need your bullpen.”

The Cardinals manager said Ryan Franklin and Russ Springer will split the closing duties and that the St. Louis skipper wouldn’t shy from using a left-hander in the role against certain lineups.

“We’ll mix and match,” La Russa said. “I think all things, everyone rested, Franklin and Springer are the guys that match up the best.”

Franklin, who had been the setup man, said he hadn’t been told what his new role might be, but the right-hander is 1-1 with a 2.00 ERA in 19 appearances this season.

“He gets righties and lefties out, he’s very quick off the mound, so he’s tough to run on,” La Russa said. “He gives you a lot as a guy that’s pitching important innings in games.”

Isringhausen, who has four blown save opportunities in his past seven appearances and is 1-4 with a 7.47 ERA, said Saturday he met with La Russa and agreed he needed to be pulled from the role.

“It needed to be done,” he said. “It’s a mental break more than anything.”

Isringhausen, who leads the NL with 11 saves and is eight saves shy of 300 for his career, was clearly upset after Friday’s game, putting all the blame on himself.

“I’m just getting sick of embarrassing myself and letting my team down,” he said Friday night. “We should be five more wins in the win column in my mind, so we should be ahead in first place even more. But they can’t keep sending me out there when I’m pitching the way I’m pitching.

“We’re going to have to figure out some kind of remedy. I’m sure that remedy will give me some time off and get somebody in there that can do a better job right now. ... I’m just pitching like a second grader.”

La Russa told Isringhausen on Saturday that it’s no different from when a top hitter is struggling in the lineup. La Russa’s only options would be to shuffle the lineup or give a player a few days on the bench.